Giloy benefits
Giloy (Tinospora cordifolia) has been regarded as the most significant and powerful therapeutic substance in Ayurvedic writings. For millennia, giloy leaves have been used to treat a variety of human illnesses. This review emphasizes how giloy leaves can be utilized to create functional food products and have immunomodulatory qualities. The phytochemical content of giloy leaves and the mechanism behind their immunomodulatory impact are the main topics of the current review. Particular pathways that are highlighted include the NF-kB pathway and interleukin regulation. Giloy leaves have antioxidant properties and trigger immune response-induced cell death. Research has demonstrated the possibility of using giloy leaves to combine ancient knowledge with contemporary functional food manufacturing in a variety of value-added products, including beverages, biscuits, and herbal formulations.
Giloy leaf extract relieves liver-related problems like hepatitis as well as digestive disorders like acidosis, gastroenteritis, parasite infections, nausea, stomach discomfort, and excessive thirst.
According to the most recent research, the immunomodulatory properties of giloy leaves may be linked to their many possible applications. The body’s immune response may be strengthened by these traits, offering a natural way to support overall health [8]. Although giloy leaves have several traditional medical use, little is known about their immunomodulatory properties.
Finding pertinent research
An extensive investigation on the immunomodulatory properties of giloy (Tinospora cordifolia) leaves has been conducted by a methodical search of important electronic databases, including PubMed, Scopus, and Google Scholar. Several phrases that covered several facets of immune system regulation and potential applications were included in the search method. In addition to terms on general immunomodulatory effects, cellular mechanisms of the immune response, and product development (such as “cytokines,” “macrophages,” and “natural killer cells”), as well as terms pertaining to immune system function and anti-inflammatory properties, terms like “Tinospora cordifolia” or “Giloy leaves” were used here.
The inclusion and exclusion strategy
Research that elucidates the mechanisms of action by which giloy (Tinospora cordifolia) leaves impact the immune system is the main emphasis of the two-tiered selection approach used for the review. The highlighted study looks at how Tinospora cordifolia impacts immune cells or function in lab-based or animal models. It is published in peer-reviewed academic journals and offers convincing proof of Tinospora cordifolia’s mechanisms of action on immunological function, including the role of particular bioactive compounds that are extracted from its leaves.
All things considered, giloy leaves are considered a natural immunomodulatory agent with a host of additional qualities, including hepatoprotective, anti-inflammatory, and antioxidant, all of which necessitated further investigation by the researchers to fully comprehend.
